BDBM50505256 CHEMBL4547737

SMILES [H][C@@]12NC(=N)N[C@]11N(CCC1(O)O)C(=N)N[C@H]2COC(C)=O

InChI Key InChIKey=FYMGGEYPNDYSSU-HFJPGXAFSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50505256   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)
Affinity DataIC50:  19nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)
Affinity DataIC50:  4.57E+3nMAssay Description:Inhibition of recombinant human Nav1.5 expressed in CHO cells by whole cell voltage clamp electrophysiology recordingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)
Affinity DataIC50:  83nMAssay Description:Inhibition of recombinant rat Nav1.4 expressed in CHO cells by whole cell voltage clamp electrophysiology recordingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics

Curated by ChEMBL
LigandPNGBDBM50505256(CHEMBL4547737)
Affinity DataIC50:  18nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell patch clamp electrophysiology recordingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed