BDBM50505257 CHEMBL4471012
SMILES C[C@@H](N1CC[C@H](C1)n1nc(C)c2cc(C(=O)NS(=O)(=O)C3CC3)c(F)cc12)c1cc(Cl)cc(Cl)c1
InChI Key InChIKey=KQQXPTRMUYKUIC-RDTXWAMCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50505257
TargetSodium channel protein type 10 subunit alpha(Mus musculus)
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 2.20E+4nMAssay Description:Binding affinity to mouse Nav1.8 TTX-resistant current by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 7 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 22nMAssay Description:Binding affinity to human recombinant Nav1.7 by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to human recombinant Nav1.1 by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 3 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 110nMAssay Description:Binding affinity to human recombinant Nav1.3 by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 47nMAssay Description:Binding affinity to human recombinant Nav1.4 by radioligand binding assayMore data for this Ligand-Target Pair
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 620nMAssay Description:Binding affinity to human recombinant Nav1.6 by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 460nMAssay Description:Binding affinity to human recombinant Nav1.5 by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 14nMAssay Description:Binding affinity to mouse Nav1.7 by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataIC50: 435nMAssay Description:Concentration at which the clotting time was prolonged by twice that of the control by inhibiting thrombinMore data for this Ligand-Target Pair
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Siteone Therapeutics
Curated by ChEMBL
Siteone Therapeutics
Curated by ChEMBL
Affinity DataKd: 140nMAssay Description:Binding affinity to human recombinant Nav1.2 by radioligand binding assayMore data for this Ligand-Target Pair