BDBM50505516 CHEMBL4566413

SMILES CC[C@H](C)[C@H](NC(=O)C(CO)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)[C@@H](C)CC)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(O)=O

InChI Key InChIKey=UNSNIYPFYFPYIH-OFFVXGIUSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50505516   

TargetBTB/POZ domain-containing protein KCTD12(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50505516(CHEMBL4566413)
Affinity DataKi:  7.56E+3nMAssay Description:Displacement of TAMRA-AAG-SLQLPILHHAYLPSIGGV from recombinant human 6X His-tagged KCTD12 T1 domain (27 to 131 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBTB/POZ domain-containing protein KCTD12(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50505516(CHEMBL4566413)
Affinity DataIC50:  2.55E+4nMAssay Description:Displacement of TAMRA-AAG-SLQLPILHHAYLPSIGGV from recombinant human 6X His-tagged KCTD12 T1 domain (27 to 131 residues) expressed in Escherichia coli...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBTB/POZ domain-containing protein KCTD12(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50505516(CHEMBL4566413)
Affinity DataEC50:  750nMAssay Description:Binding affinity to recombinant human 6X His-tagged KCTD12 T1 domain (27 to 131 residues) expressed in Escherichia coli BL21 DE3 cells preincubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed