BDBM50505634 CHEMBL4569453

SMILES Cl.CN(C)S(=O)(=O)c1ccc(OCc2cn(C\C(F)=C\CN)nn2)cc1

InChI Key InChIKey=JDEAGHMESKXNSD-OZLKFZLXSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50505634   

TargetLysyl oxidase homolog 2(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50:  50nMAssay Description:Inhibition of recombinant human C-terminal His-tagged LOLX2 (1-774 residues) expressed in mouse myeloma cells using putrescine as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein-lysine 6-oxidase(Bos taurus)
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50:  794nMAssay Description:Inhibition of LOX in bovine aorta using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50: <3.16E+4nMAssay Description:Inhibition of recombinant human SSAO using benzylamine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD-amino-acid oxidase(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50:  316nMAssay Description:Inhibition of recombinant human DAO using putrescine as substrate preincubated with enzyme for 30 mins followed by substrate addition and measured ev...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Pharmaxis

Curated by ChEMBL
LigandPNGBDBM50505634(CHEMBL4569453)
Affinity DataIC50:  126nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected in BTI cells using benzylamine as substrate preincubated with enzyme for 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed