BDBM50505701 CHEMBL4544086

SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2ccc(F)cc2)c2ccccc2)CC1

InChI Key InChIKey=UDYXSPVICNNUPJ-UHFFFAOYSA-N

Data  18 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50505701   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  0.550nMAssay Description:Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H] prazosin from alpha1A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  34nMAssay Description:Displacement of [3H] WAY100635 from 5HT1A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  110nMAssay Description:Displacement of [3H] Spiperone from human D2S receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  130nMAssay Description:Displacement of [3H] Ketanserin from 5HT2A receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  140nMAssay Description:Displacement of [3H] Spiperone from human D2L receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  310nMAssay Description:Displacement of [3H] Spiperone from human D3 receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  360nMAssay Description:Displacement of [3H] SCH23390 from D1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  860nMAssay Description:Displacement of [3H] RX821002 from alpha2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H] SCH23390 from D5 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H] diprenorphine from mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  4.30E+3nMAssay Description:Displacement of [3H] diprenorphine from kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  4.50E+3nMAssay Description:Displacement of [3H] CGP12177 from beta2 adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  1.50E+4nMAssay Description:Displacement of [3H] NMS from muscarinic M1 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  1.70E+4nMAssay Description:Displacement of [3H] NMS from muscarinic M2 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  1.90E+4nMAssay Description:Displacement of [3H] diprenorphine from delta opioid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi:  3.70E+4nMAssay Description:Displacement of [3H] NMS from muscarinic M3 receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H] CGP12177 from beta1 adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human D4 receptor expressed in HEK293T cells co-expressing G-alphaqi assessed as accumulation of inositol monophosphate using d2-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataIC50:  620nMAssay Description:Antagonist activity at PKA-tagged D4 receptor (unknown origin) expressed in HEK293 cells co-expressing beta-arrestin2 assessed as inhibition of quinp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50505701(CHEMBL4544086)
Affinity DataEC50:  500nMAssay Description:Agonist activity at PKA-tagged D4 receptor (unknown origin) expressed in HEK293 cells co-expressing beta-arrestin2 assessed as induction of beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed