BDBM50505789 CHEMBL4471621

SMILES COc1ccc(cc1)[C@@H]1N(CCc2sccc12)C(=O)Nc1cc(Cl)cc(Cl)c1

InChI Key InChIKey=VPDBRKAZMIEIGB-FQEVSTJZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50505789   

TargetLutropin-choriogonadotropic hormone receptor(Rattus norvegicus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50505789(CHEMBL4471621)
Affinity DataIC50:  412nMAssay Description:Antagonist activity at rat luteinizing hormone receptor expressed in rat ovary granulosa GLHR15 cell suspension assessed as reduction in agonist-indu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C11(Rattus norvegicus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50505789(CHEMBL4471621)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human thyroid stimulating hormone receptor expressed in rat HTC133 cells assessed as reduction in agonist-induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLutropin-choriogonadotropic hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505789(CHEMBL4471621)
Affinity DataIC50:  403nMAssay Description:Antagonist activity at human luteinizing hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFollicle-stimulating hormone receptor(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50505789(CHEMBL4471621)
Affinity DataIC50: >1.65E+4nMAssay Description:Antagonist activity at human follicle stimulating hormone receptor assessed as reduction in agonist-induced cAMP production preincubated for 20 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLutropin-choriogonadotropic hormone receptor(Mus musculus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50505789(CHEMBL4471621)
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at luteinizing hormone receptor in mouse MLTC-1 cells assessed as reduction in agonist-induced cAMP production preincubated for 3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed