BDBM50508743 CHEMBL4460141

SMILES CC(=O)Nc1ncc(CN2CCC3(CCN(C3)c3ncc(C)cc3C)C2)s1

InChI Key InChIKey=RROPSOUKMJSJQR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508743   

TargetProtein O-GlcNAcase(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508743(CHEMBL4460141)
Affinity DataIC50:  209nMAssay Description:Inhibition of OGA in HEK293 cells assessed as increase in O-GlcNAcylated protein level by Hoechst staining based microscopic methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein O-GlcNAcase(Homo sapiens (Human))
Drexel University

Curated by ChEMBL
LigandPNGBDBM50508743(CHEMBL4460141)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of recombinant human full length OGA using FM-GlcNAc as substrate preincubated for 60 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed