BDBM50510979 CHEMBL4575752
SMILES [H][C@@]12C[C@]1(CO)SC(N)=N[C@]2(C)c1cc(NC(=O)c2ccc(Cl)cn2)cc(F)c1F
InChI Key InChIKey=SYUXGKTZZPXWFX-GDIGMMSISA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50510979
Affinity DataIC50: 2.40nMAssay Description:Inhibition of BACE1 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...More data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of BACE2 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of BACE in HEK293 cells harboring APP Swedish mutant assessed as reduction in amyloid beta 40 level measured after overnight incubation by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.25E+6nMAssay Description:Inhibition of recombinant CatD (unknown origin) expressed in CHO cells using FRET peptide substrate preincubated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair