BDBM50510989 CHEMBL4593414
SMILES [H][C@@]12C[C@]1(COC)SC(N)=N[C@]2(C)c1cc(NC(=O)c2cnc(OCC)cn2)cc(F)c1F
InChI Key InChIKey=JMBJLUDMTZCGCO-IWMITWMQSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50510989
Affinity DataIC50: 4.20nMAssay Description:Inhibition of BACE in HEK293 cells harboring APP Swedish mutant assessed as reduction in amyloid beta 40 level measured after overnight incubation by...More data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Inhibition of BACE2 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of BACE1 (unknown origin) using FRET peptide substrate preincubated for 1 hr followed by substrate addition and measured after 1 hr by FRE...More data for this Ligand-Target Pair