BDBM50511376 CHEMBL4516665

SMILES O=C(Nc1n[nH]c2cc(ccc12)-c1cccc(NS(=O)(=O)C2CC2)c1)C1CC1

InChI Key InChIKey=HJDMEPOCEJXNJU-UHFFFAOYSA-N

Data  4 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50511376   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataKi:  8.30nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged AAK1 kinase domain (31 to 396 residues) (unknown origin)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBMP-2-inducible protein kinase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataKi:  13nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged BMP2K kinase domain (38 to 345 residues) (unknown origin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSerine/threonine-protein kinase 16(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataKi:  330nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged STK16 kinase domain (13 to 305 residues) (unknown origin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged GAK kinase domain (12 to 347 residues) (unknown origin) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataIC50:  641nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused AAK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by N...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetBMP-2-inducible protein kinase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused BMP2K (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataIC50:  31nMAssay Description:Inhibition of AAK1 (unknown origin) using Fos-Nfluc, Cfluc-kinase and rabbit reticulate lysate system after 1 hr by split luciferase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused GAK (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by Na...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 16(Homo sapiens (Human))
University Of North Carolina At Chapel Hill (Unc-Ch)

Curated by ChEMBL
LigandPNGBDBM50511376(CHEMBL4516665)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of tracer K5 binding to N-terminal nano luciferase-fused STK16 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed