BDBM50511507 CHEMBL4442011

SMILES [H][C@@]12Cc3ccc(OC)c(OC)c3-c3ccc(CC)c(CCN1C)c23

InChI Key InChIKey=FTEACBHSVWHXQR-KRWDZBQOSA-N

Data  8 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50511507   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  505nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  617nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  247nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50:  1.51E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50: <1.00E+4nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  501nMAssay Description:Agonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP Glo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  251nMAssay Description:Agonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arresti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataEC50:  614nMAssay Description:Agonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50: <1.00E+4nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at D2 long receptor (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at D1R (unknown origin) transfected in human HEK293T cells assessed as increase in cAMP accumulation incubated for 2 hrs by cAMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50:  41nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D2 long receptor (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tag...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Duke University

Curated by ChEMBL
LigandPNGBDBM50511507(CHEMBL4442011)
Affinity DataIC50:  1.52E+3nMAssay Description:Antagonist activity at C-terminal RLuc8-fused D1R (unknown origin) transfected in human HEK293T cells co-expressing N-terminal Venus-tagged beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed