BDBM50512070 CHEMBL4443462

SMILES ONC(=O)CCCCCCn1cc(Nc2ncc(Cl)c(Nc3ccccc3)n2)cn1

InChI Key InChIKey=ZJQBOUFZLSVUBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512070   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512070(CHEMBL4443462)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human JAK2 using Ulight-CAGAGAIETDKEYYTVKD as substrate measured after 60 mins by LANCE assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50512070(CHEMBL4443462)
Affinity DataIC50:  19nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed