BDBM50512453 CHEMBL4437772

SMILES Cn1ccc(n1)-c1cc(ccc1C(F)(F)F)C(=O)Nc1c(nc2ccc(cn12)C(C)(C)O)-c1ccccc1

InChI Key InChIKey=SAERRKQFCAUMTN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50512453   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50512453(CHEMBL4437772)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of recombinant full length human TRKA expressed in U2OS cells using Poly(Glu:Tyr) as substrate after 30 mins by scintillation counting ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed