BDBM50512566 CHEMBL4444708

SMILES [H][C@]12[#6]-[#16]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#6]-[#8]-c3ccc4[se;v2]n(-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-n5[se;v2]c6ccc(-[#8]-[#6])cc6c5=O)c(=O)c4c3)[C@@]1([H])[#7]-[#6](=O)-[#7]2

InChI Key InChIKey=URPCJZKVOUNFJB-VBOOUTDYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512566   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50512566(CHEMBL4444708)
Affinity DataKd:  142nMAssay Description:Binding affinity to human KGA assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50512566(CHEMBL4444708)
Affinity DataIC50:  73nMAssay Description:Allosteric inhibition of human KGA assessed as reduction in glutamate formation using glutamine as substrate pretreated with enzyme for 15 mins follo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed