BDBM50512726 CHEMBL4459950

SMILES CC[C@@H](CC(O)=O)c1cccc(NC(=O)C(C2CCCC2)c2ccc(cc2)-c2cncc(CC(C)C)c2)c1C

InChI Key InChIKey=OYYPUWHVMWNOPI-CPMFFWQLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50512726   

TargetProstaglandin E synthase(Homo sapiens (Human))
Bayer

Curated by ChEMBL
LigandPNGBDBM50512726(CHEMBL4459950)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Mus musculus)
Bayer

Curated by ChEMBL
LigandPNGBDBM50512726(CHEMBL4459950)
Affinity DataIC50:  84nMAssay Description:Inhibition of mouse recombinant FLAG-tagged PTGES expressed in baculovirus infected Hi-5 insect cells using prostaglandin H2 as substrate incubated f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed