BDBM50514307 CHEMBL4457158

SMILES CCC(=O)c1sc(c(C)c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1

InChI Key InChIKey=DYIIYIJHDMIABW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514307   

TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50514307(CHEMBL4457158)
Affinity DataEC50:  320nMAssay Description:Positive allosteric modulation of human alpha7 nAChR in human IMR-32 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50514307(CHEMBL4457158)
Affinity DataEC50:  324nMAssay Description:Positive allosteric modulatory activity against alpha7 nAChR in human IMR-32 cells assessed as potentiation of PNU-282987-induced Ca2+ efflux at by F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed