BDBM50514307 CHEMBL4457158
SMILES CCC(=O)c1sc(c(C)c1-c1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1
InChI Key InChIKey=DYIIYIJHDMIABW-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50514307
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 320nMAssay Description:Positive allosteric modulation of human alpha7 nAChR in human IMR-32 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 324nMAssay Description:Positive allosteric modulatory activity against alpha7 nAChR in human IMR-32 cells assessed as potentiation of PNU-282987-induced Ca2+ efflux at by F...More data for this Ligand-Target Pair