BDBM50514980 CHEMBL4438255

SMILES Nc1nnc(s1)N1CC[C@H](C1)Nc1nnc(NC(=O)Cc2ccccc2)s1

InChI Key InChIKey=XEPCFWCPQXKTNL-LLVKDONJSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50514980   

TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of GLS2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50514980(CHEMBL4438255)
Affinity DataIC50:  347nMAssay Description:Inhibition of recombinant 6His-tagged GLS1 KGA isoform (unknown origin) (63 to 669 residues) expressed in Escherichia coli using glutamine as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB