BDBM50515042 CHEMBL4593398
SMILES FC(F)(F)c1n[nH]cc1-c1nc2ccc3[nH]ncc3c2c2CCCCc12
InChI Key InChIKey=VWBUFGGJMMUSBL-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50515042
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin) using MBP as substrate after 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin) using MBP as substrate after 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetLymphokine-activated killer T-cell-originated protein kinase(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of TOPK (unknown origin) using MBP as substrate after 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetLymphokine-activated killer T-cell-originated protein kinase(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of TOPK (unknown origin) autophosphorylation measured after 3 hrs by multi-mode microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 (unknown origin) autophosphorylation measured after 3 hrs by multi-mode microplate readerMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3 (unknown origin) using MBP as substrate after 3 hrs by ADP-Glo assayMore data for this Ligand-Target Pair