BDBM50515566 CHEMBL4475538
SMILES CN1c2ccccc2Sc2cc(\C=C3\SC(=S)N(CC(=O)OCC4COC(C)(C)O4)C3=O)ccc12
InChI Key InChIKey=IPHJRUZANDHSCX-SRZZPIQSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50515566
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Guangdong University Of Technology
Curated by ChEMBL
Guangdong University Of Technology
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation in human SH-SY5Y cells incubated for 48 hrs by fluorescence microscopyMore data for this Ligand-Target Pair
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Guangdong University Of Technology
Curated by ChEMBL
Guangdong University Of Technology
Curated by ChEMBL
Affinity DataKd: 25nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair