BDBM50516046 CHEMBL4455665

SMILES O=C(Oc1cccc(c1)N1CCS(=O)(=O)CC1)N1CCN(Cc2cccc(c2)-c2ccccc2)CC1

InChI Key InChIKey=OHHURVPXRFSQKN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516046   

TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516046(CHEMBL4455665)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human recombinant MBP-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516046(CHEMBL4455665)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged MGL expressed in Escherichia coli BL21 DE3 cells using AHMMCE as substrate preincubated with enzyme for 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50516046(CHEMBL4455665)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of rat recombinant His/GST-tagged FAAH expressed in Escherichia coli cells using AAMCA as substrate incubated for 15 mins followed by subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed