BDBM50516547 CHEMBL4448045::US10899738, Cpd. No 27

SMILES N#Cc1ccc(OCCCN2CCC(CC2)C2(NCCc3ccccc23)C2CCCC2)cc1

InChI Key InChIKey=IUELPAAABCQQDW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516547   

TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516547(CHEMBL4448045 | US10899738, Cpd. No 27)
Affinity DataKi:  22nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516547(CHEMBL4448045 | US10899738, Cpd. No 27)
Affinity DataIC50:  71nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516547(CHEMBL4448045 | US10899738, Cpd. No 27)
Affinity DataIC50:  71nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent