BDBM50516572 CHEMBL4532417::US10899738, Cpd. No 52

SMILES O=S(=O)(c1ccncc1)c1ccc(cc1)N1CC(CN2CCC(CC2)C2(CN(CC3COC3)Cc3ccccc23)C2CCCC2)C1

InChI Key InChIKey=AUGOJKCHJPNYFD-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50516572   

TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516572(CHEMBL4532417 | US10899738, Cpd. No 52)
Affinity DataKi:  7nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516572(CHEMBL4532417 | US10899738, Cpd. No 52)
Affinity DataIC50:  25nMAssay Description:Inhibition of FAM-probe binding to Menin (unknown origin) after 60 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMenin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50516572(CHEMBL4532417 | US10899738, Cpd. No 52)
Affinity DataIC50:  25nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent