BDBM50516598 CHEMBL475232::US11059801, Compound D-61
SMILES [O-][N+](=O)c1ccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2c1
InChI Key InChIKey=MYPNWKPZEHVONN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50516598
TargetCereblon isoform 4(Magnetospirillum gryphiswaldense)
Max Planck Institute For Developmental Biology
Curated by ChEMBL
Max Planck Institute For Developmental Biology
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibition of MANT-uracil binding to wild-type Magnetospirillum gryphiswaldense CRBN isoform 4 by FRET assayMore data for this Ligand-Target Pair
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 2.66E+3nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair
TargetDNA damage-binding protein 1/Protein cereblon(Homo sapiens (Human))
Dana-Farber Cancer Institute
US Patent
Dana-Farber Cancer Institute
US Patent
Affinity DataIC50: 4.13E+3nMAssay Description:A thalidomide competition AlphaScreen assay was employed to measure the binding affinity (IC50) of thalidomide conjugates and novel IMiDs to CRBN-DDB...More data for this Ligand-Target Pair