BDBM50517604 CHEMBL4513509

SMILES [H][C@]12CCCC[C@@]1([H])[C@H](C[C@H](NC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)CN1CCOCC1)C(=O)[C@@]1(C)CO1)CCC2

InChI Key InChIKey=IJXUVRJYZJRYCL-DCGCUPEZSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50517604   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50:  2.84E+4nMAssay Description:Inhibition of 20S immunoproteasome beta 5 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 20S constitutive proteasome beta 5 chymotrypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of 20S constitutive proteasome beta 1 caspase-like activity in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50:  159nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in intact human RPMI8226 cells after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50:  190nMAssay Description:Inhibition of 20S immunoproteasome beta 2 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Leiden Institute Of Chemistry And Netherlands Proteomics Centre

Curated by ChEMBL
LigandPNGBDBM50517604(CHEMBL4513509)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 20S immunoproteasome beta 1 in human Raji cell lysates after 1 hr by competitive ABPP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed