BDBM50517942 CHEMBL4475286

SMILES CCOC(=O)NC(=O)c1ccsc1NC(=O)c1ccn2cnnc2c1

InChI Key InChIKey=LUOJPVWKDGFANM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50517942   

TargetDecaprenylphosphoryl-beta-D-ribose oxidase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Maharaja Sayajirao University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50517942(CHEMBL4475286)
Affinity DataIC50:  60nMAssay Description:Inhibition of N-terminal His6-thioredoxin tagged Mycobacterium tuberculosis H37Rv DprE1 expressed in Escherichia coli BL21(DE3) using FPR as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
The Maharaja Sayajirao University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50517942(CHEMBL4475286)
Affinity DataIC50:  1.83E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 30 mins by in presence of NADPH by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed