BDBM50518240 CHEMBL4439523
SMILES CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N2
InChI Key InChIKey=NMQUIMIHINHOMQ-FROOAQRNSA-N
Data 12 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50518240
Affinity DataKi: 0.0510nMAssay Description:Inhibition of human plasmin using Ac-RM(O2)YR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 160nMAssay Description:Inhibition of bovine cationic trypsin using Bz-FVR-pNA as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+4nMAssay Description:Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate after 30 minsMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of activated beta-factor 11 (unknown origin) using Bz-FVRpNA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of plasma KLK (unknown origin) using Ac-NLTR-pNA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of matriptase (unknown origin) using Boc-QAR-MCA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of activated factor 10 (unknown origin) using Ac-QRSR-pNA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
TargetTissue-type plasminogen activator(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using Z-Pyr-Gly-Arg-MCA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of activated beta-factor 12 (unknown origin) using Ac-QRFR-pNA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human thrombin using Ac-ATPR-pNA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of activated beta-factor 9 (unknown origin) using Boc-QGR-MCA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
The University Of Queensland
Curated by ChEMBL
The University Of Queensland
Curated by ChEMBL
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of uPA (unknown origin) using Z-Pyr-Gly-Arg-MCA as substrate after 30 mins relative to untreated controlMore data for this Ligand-Target Pair