BDBM50518504 CHEMBL4466764

SMILES NC(=O)c1cc(Cl)c2c(Cl)c(C#CC3COCCO3)n([C@H]3CCCNC3)c2n1

InChI Key InChIKey=NFWRERNMTFKQTQ-PXYINDEMSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518504   

TargetSerine/threonine-protein kinase pim-1/pim-2/pim-3(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50518504(CHEMBL4466764)
Affinity DataEC50:  70nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1/pim-2/pim-3(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50518504(CHEMBL4466764)
Affinity DataEC50:  70nMAssay Description:Inhibition of PIM in human KG1 cells assessed as reduction in pS6 levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed