BDBM50519468 CHEMBL4440241

SMILES C1CCN(C1)c1nc2ccccc2[nH]1

InChI Key InChIKey=RXWCRIKVVODMRG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50519468   

TargetShort transient receptor potential channel 4(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of mouse TRPC4 beta expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 5(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of mouse TRPC5 expressed in HEK293 cells co-expressing mu-opioid receptor assessed as reduction in DAMGO-induced membrane potential by FMP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human TRPC3 expressed in HEK293 cells assessed as reduction in carbachol-induced membrane potential by FMP-2 dye based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetShort transient receptor potential channel 6(Mus musculus)
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50519468(CHEMBL4440241)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of mouse TRPC6 expressed in HEK293 cells co-expressing M5 receptor assessed as reduction in carbachol-induced membrane potential by FMP-2 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed