BDBM50519567 CHEMBL4476024
SMILES CCN(c1cnc(C(=O)[C@H]2C[C@@H]2C(O)=O)c(OC)c1)c1ccc(F)c2ccccc12
InChI Key InChIKey=WZZGQVYQQSYOEW-IRXDYDNUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50519567
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human N-terminal His6-tagged LTC4S expressed in Pichia pastoris X33 using LTA4 methyl ester and glutathione as substrate preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of LTC4S in zymosan-stimulated human PBMC assessed as inhibition of LTC4 production preincubated for 45 mins followed by zymosan stimulati...More data for this Ligand-Target Pair