BDBM50519589 CHEMBL4531985
SMILES CCN(c1cccc(c1)C(F)(F)F)c1cnc(C(=O)[C@H]2C[C@@H]2C(O)=O)c(OC)c1
InChI Key InChIKey=IPERJOIIXBXGGP-GJZGRUSLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50519589
Affinity DataIC50: 13nMAssay Description:Inhibition of human N-terminal His6-tagged LTC4S expressed in Pichia pastoris X33 using LTA4 methyl ester and glutathione as substrate preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibition of LTC4S in zymosan-stimulated human PBMC assessed as inhibition of LTC4 production preincubated for 45 mins followed by zymosan stimulati...More data for this Ligand-Target Pair