BDBM50519624 CHEMBL4468645

SMILES [H][C@@]12CC[C@H]1CN1C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc13)C(=O)NS(=O)(=O)[C@H](C)CC\C=C\[C@@H]2O

InChI Key InChIKey=BHVJUQVROJMZJB-MQTRKTCISA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50519624   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50519624(CHEMBL4468645)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and biotinylated Bim BH3 peptide interaction usi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50519624(CHEMBL4468645)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB