BDBM50520291 CHEMBL4450463
SMILES CC(C)Oc1cc(ccc1C(N)=O)-c1cccnc1
InChI Key InChIKey=DZEKKRSPIVXYAJ-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50520291
TargetMAP kinase-interacting serine/threonine-protein kinase 1/2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 880nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair