BDBM50520571 CHEMBL4447794

SMILES CN(c1cccc(CNc2nc(Nc3ccc(OCCOCCC(=O)N[C@H](C(=O)N4C[C@H](O)C[C@H]4C(=O)NCc4ccc(cc4)-c4scnc4C)C(C)(C)C)cc3)ncc2C(F)(F)F)c1)S(C)(=O)=O

InChI Key InChIKey=MVULIYLBRNHLEE-LFHXYJAASA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50520571   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human recombinant FAK using poly[Glu:Tyr] (4:1) substrate in presence of 10 mM ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataEC50:  3nMAssay Description:Induction of degradation of Fak in human PC-3 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human FAK using poly (Glu,Tyr) as substrate by radiometric HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed