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Found 4 Enz. Inhib. hit(s) with Target = 'Focal adhesion kinase 1' and Ligand = 'BDBM50520571'
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human recombinant FAK using poly[Glu:Tyr] (4:1) substrate in presence of 10 mM ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of FAK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of human FAK using poly (Glu,Tyr) as substrate by radiometric HotSpot kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50520571(CHEMBL4447794)
Affinity DataEC50:  3nMAssay Description:Induction of degradation of Fak in human PC-3 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed