BDBM50521269 CHEMBL4591657

SMILES COc1ccc(F)c(c1)[C@H]1CC[C@H](COc2cccc(c2)[C@@H](CC(O)=O)C2CC2)CC1

InChI Key InChIKey=HIODEEANJKNPJV-LTMIRXACSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50521269   

TargetMelanocortin receptor 4(Rattus norvegicus)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521269(CHEMBL4591657)
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at rat GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521269(CHEMBL4591657)
Affinity DataEC50:  0.940nMAssay Description:Agonist activity at human GPR40 expressed in HEK293 cells assessed as induction of intracellular calcium mobilization by Fluo-8 dye based FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521269(CHEMBL4591657)
Affinity DataEC50:  199nMAssay Description:Agonist activity at human GPR40 expressed in CHOK1 cells assessed as induction of Galphaq-mediated IP1 accumulation after 90 mins HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Homo sapiens (Human))
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50521269(CHEMBL4591657)
Affinity DataEC50:  1.37E+3nMAssay Description:Agonist activity at GPR40 in human islets assessed as induction of glucose-stimulated insulin secretion after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed