BDBM50522493 CHEMBL4530083
SMILES NC(=N)c1ccc(NCc2nc(c[nH]2)-c2ccccc2)cc1OCc1cccnc1
InChI Key InChIKey=ZDLCAMFQMDNCSU-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50522493
Affinity DataIC50: 794nMAssay Description:Inhibition of recombinant C-terminal 10-His tagged human KLK8 (Gln29 to Gly260 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human KLK14 (Gln19 to Met248 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrate ...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human coagulation factor 10a (Leu24 to Lys488 residues) expressed in baculovirus infected Sf9 insec...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human thrombin (Met1 to Glu622 residues) expressed in mouse NS0 cells using BOC-VPR-AMC as substrat...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 40 mins by fluorescence intensity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant 6His-Q-FLAG tagged human KLK5 expressed in baculovirus infected Sf9 insect cells using (Tos-Gly-Pro-Arg)2[R110].2TFA as sub...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human KLK7 (Glu23 to His252 residues) expressed in mouse NS0 cells using 5-FAM-E-A-L-Y-L-V-S-G-C as...More data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human N-terminal met-His6-tagged matriptase catalytic domain (Gly596 to Val855 residues) expressed in Escherichia coli usin...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Glaxosmithkline R&D
Curated by ChEMBL
Glaxosmithkline R&D
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of recombinant C-terminal 10His-tagged human urokinase (Met1 to Leu431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant C-terminal 6-His tagged human KLKB1 (Gly20 to Ala638 residues) expressed in mouse NS0 cells using P-F-R-AMC as substrate af...More data for this Ligand-Target Pair
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of recombinant bovine enterokinase activated N-terminal His-tagged recombinant human KLK1 (19 to 262 residues) expressed in baculovirus in...More data for this Ligand-Target Pair