BDBM50522514 CHEMBL4554796
SMILES CCn1cc(-c2c(Cl)cccc2Cl)c(=O)c2cnc(Nc3ccc4c(CN(C)CC44CC4)c3)nc12
InChI Key InChIKey=YFILBGQGKRVKDL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50522514
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research And Development
Curated by ChEMBL
Global Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to wild type N-terminal GST-tagged human WEE1 catalytic domain (215 to 646 residues) expressed in baculovirus expression system meas...More data for this Ligand-Target Pair
TargetWee1-like protein kinase(Homo sapiens (Human))
Global Pharmaceutical Research And Development
Curated by ChEMBL
Global Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Inhibition of WEE1 in human NCI-H1299 cells assessed as reduction in Cdc2 phosphorylation at Tyr15 residue measured after 6 hrs by ELISAMore data for this Ligand-Target Pair