BDBM50523489 CHEMBL4518093

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1CCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O

InChI Key InChIKey=SRDZGAINBRYGQH-VZMVMXEKSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50523489   

TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataKi:  39nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged G9a (913 to 1193 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using H3-21 peptide as substrate prei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Rattus norvegicus)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of rat His6-tagged PRMT1 expressed in Escherichia coli BL21(DE3) using H4-21 peptide as substrate preincubated for 10 mins in presence of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase SETD7(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged SETD7 (1 to 366 residues) expressed in Escherichia coli using H3-21 peptide as substrate preincubated for 10 mins in p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50:  158nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteinase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SAHH (unknown origin) using SAH as substrate preincubated for 10 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-terminal Xaa-Pro-Lys N-methyltransferase 1(Homo sapiens)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50:  35nMAssay Description:Inhibition of recombinant human full-length His6-tagged NTMT1 (1 to 222 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL competent cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNicotinamide N-methyltransferase(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50523489(CHEMBL4518093)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human His-tagged NNMT (1 to 264 residues) expressed in Escherichia coli BL21(DE3) using 1-quinoline as substrate preincubated for 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed