BDBM50523500 CHEMBL4555776

SMILES OC[C@H]1CCCN1Cc1ccc(COc2cccc(OCc3ccc(cc3)C#N)c2)cc1

InChI Key InChIKey=RXMXSKGMPSEPOQ-RUZDIDTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50523500   

TargetSphingosine kinase 2(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50523500(CHEMBL4555776)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal His-tagged SK2 expressed in baculovirus infected Sf9 insect cells using Sph as substrate measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Heriot-Watt University

Curated by ChEMBL
LigandPNGBDBM50523500(CHEMBL4555776)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of GFP-tagged SK1 (unknown origin) expressed in HEK293 cells using Sph as substrate measured after 30 mins in presence of [gamma32P]ATP by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed