BDBM50524368 CHEMBL4452406

SMILES COc1cccc(c1)-c1nc(N)nc2C(C)CCCc12

InChI Key InChIKey=GXCHTBPCLXWHRK-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50524368   

TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataEC50:  250nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataEC50:  245nMAssay Description:Agonist activity at recombinant human Gs-coupled H2 receptor expressed in HEK293T cells assessed as inhibition of forskolin-stimulated cAMP accumulat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataIC50:  66nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Academy Of Scientific And Innovative Research (Acsir)

Curated by ChEMBL
LigandPNGBDBM50524368(CHEMBL4452406)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at recombinant human Gi-coupled H3 receptor expressed in HEK293T cells assessed as reduction in histamine-induced inhibition of f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed