BDBM50527726 CHEMBL4445719
SMILES C[C@@](O)(C#Cc1ccc(F)c(c1)-c1c[nH]c2cnc(N)nc12)c1nccs1
InChI Key InChIKey=NFAPIBSJICIXGB-LJQANCHMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50527726
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged NIK (318 to 947 residues) expressed in baculovirus infected Sf9 cells using ultrapure ATP as su...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Chinese Academy Of Sciences
Curated by ChEMBL
Chinese Academy Of Sciences
Curated by ChEMBL
Affinity DataKd: 4.90nMAssay Description:Binding affinity to wild-type human partial length NIK (L318 to P947 residues) expressed in mammalian expression system by Kinomescan methodMore data for this Ligand-Target Pair