BDBM50528195 CHEMBL4435320
SMILES COc1cc(cc(OC)c1C(N)=O)-c1cncc(c1C)-c1ccc(cc1)N1CCN(C)CC1
InChI Key InChIKey=XIAQAOWQYMNJJB-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50528195
Affinity DataIC50: <3nMAssay Description:Inhibition of human ALK2 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of C-terminal nanoluciferase-fused ALK2 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by NanoBRET NanoGlo Substr...More data for this Ligand-Target Pair
Affinity DataIC50: 249nMAssay Description:Inhibition of ALK5 (unknown origin) expressed in HEK293 cells transfected with CAGA-luciferase and Renilla luciferase reporter measured after 24 hrs ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of human ALK2 R206H mutant using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 R258G mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human ALK5 using casein as substrate in presence of 10 uM [gamma33P] ATP by radioactive assayMore data for this Ligand-Target Pair
Affinity DataIC50: <2nMAssay Description:Inhibition of ALK2 G328V mutant (unknown origin)More data for this Ligand-Target Pair