BDBM50528223 CHEMBL4575736

SMILES Fc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2)cc1NC(=O)Cc1cccc(n1)C(F)(F)F

InChI Key InChIKey=NFUVBUNETZNUIB-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528223   

TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528223(CHEMBL4575736)
Affinity DataKd:  280nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528223(CHEMBL4575736)
Affinity DataKd:  220nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed