BDBM50528231 CHEMBL4540715

SMILES Fc1ccc(Oc2ccc3nc(NC(=O)C4CC4)sc3c2)cc1NC(=O)Cc1cccc(c1)C(F)(F)F

InChI Key InChIKey=SDSQERWTMKMZLA-UHFFFAOYSA-N

Data  6 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50528231   

TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  77nMAssay Description:Binding affinity to wild-type human partial length RIPK3 (M1 to Q307 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  97nMAssay Description:Binding affinity to wild-type human partial length RIPK1 (M1 to K305 residues) expressed in bacterial expression system after 1 hr by quantitative PC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  80nMAssay Description:Binding affinity to RIPK3 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  77nMAssay Description:Inhibition of human wild type RIPK3 (M1 to Q307) expressed in bacterial system by kinomescan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  100nMAssay Description:Binding affinity to RIPK1 (unknown origin) by Kinomescan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50528231(CHEMBL4540715)
Affinity DataKd:  97nMAssay Description:Inhibition of human wild type RIPK1 (M1 to K305) expressed in bacterial system by kinomescan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed