BDBM50528777 CHEMBL4455008

SMILES COP(C)(=O)NCCNc1nonc1\C(Nc1ccc(F)c(c1)C#N)=N\O

InChI Key InChIKey=PPJGIMHETAHBGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50528777   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528777(CHEMBL4455008)
Affinity DataIC50:  101nMAssay Description:Inhibition of recombinant N-terminal His-tagged human IDO1 expressed in Escherichia coli assessed as reduction in N-formylkynurenine formation using ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Nanjing Medical University

Curated by ChEMBL
LigandPNGBDBM50528777(CHEMBL4455008)
Affinity DataIC50:  24nMAssay Description:Inhibition of IDO1 in human HeLa cells using L-tryptophan as substrate incubated for 48 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed