BDBM50529746 CHEMBL4589625

SMILES COc1ccc(CCc2nnc(-c3ccc(OC(C)(C)C(=O)Nc4cnn(C)c4)cc3)n2Cc2ccccc2)cc1

InChI Key InChIKey=QYUNLNGTVRYMFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50529746   

TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50529746(CHEMBL4589625)
Affinity DataIC50:  34nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50529746(CHEMBL4589625)
Affinity DataIC50:  34nMAssay Description:Inhibition of N-terminal His6-tagged PDEdelta (unknown origin) expressed in Escherichia coli BL21(DE3)-condon plus-RIL cells after 4 hrs by fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed