BDBM50530430 CHEMBL4460561
SMILES Cc1nc2ccc(nc2n1C1CC1)-c1cc(N)nc(N)c1
InChI Key InChIKey=HQAFQRVIFUNAKT-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50530430
Affinity DataIC50: 21nMAssay Description:Inhibition of CLK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of DYRK1A (unknown origin) by ADP assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of DYRK1A (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of wild type full length DYRK1A (unknown origin) in human U2OS cells assessed as reduction in pSER520 autophosphorylation incubated for 5 ...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of CLK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of DYRK1A (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 2.15E+3nMAssay Description:Inhibition of CDK9 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET as...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Servier Research Institute Of Medicinal Chemistry
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of DYRK2 (unknown origin) using Ulight-MBP as substrate and ATP as co-substrate incubated for 40 mins and measured after 1 hr by TR-FRET a...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Palack£
Curated by ChEMBL
Palack£
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of DYRK1A (unknown origin) by ADP assayMore data for this Ligand-Target Pair