BDBM50531901 CHEMBL4540813

SMILES Oc1c2cc(CP(O)(=O)c3ccccc3)cc1sc1cc(CP(O)(=O)c3ccccc3)cc(sc3cc(CP(O)(=O)c4ccccc4)cc(sc4cc(CP(O)(=O)c5ccccc5)cc(s2)c4O)c3O)c1O

InChI Key InChIKey=RHGDRBPQTMCKHX-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531901   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataKi:  140nMAssay Description:Competitive inhibition of recombinant human PTP1B expressed in Escherichia coli using varying levels of p-nitrophenol as substrate by Lineweaver-burk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  380nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TCPTP catalytic domain (2 to 315 residues) expressed in Escherichia coli using p-nitrophenol as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed