BDBM50531902 CHEMBL4569405

SMILES Oc1c2cc(CP(O)(=O)c3ccccc3)cc1S(=O)(=O)c1cc(CP(O)(=O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(O)(=O)c3ccccc3)cc(c1O)S(=O)(=O)c1cc(CP(O)(=O)c3ccccc3)cc(c1O)S2(=O)=O

InChI Key InChIKey=JNCPSODLWJEFQC-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50531902   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataKi:  32nMAssay Description:Competitive inhibition of recombinant human PTP1B expressed in Escherichia coli using varying levels of p-nitrophenol as substrate by Lineweaver-burk...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human SHP2 expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  410nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG2 catalytic domain (285 to 593 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  280nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged TCPTP catalytic domain (2 to 315 residues) expressed in Escherichia coli using p-nitrophenol as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
V.P. Kukhar Institute Of Bioorganic Chemistry And Petrochemistry Of The National Academy Of Sciences Of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)
Affinity DataIC50:  79nMAssay Description:Inhibition of recombinant human PTP1B expressed in Escherichia coli using p-nitrophenol as substrate preincubated with substrate for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed