BDBM50533243 CHEMBL4514298

SMILES COc1ccc(cc1)C1CC(=NN1C(=S)Nc1cccc(OC)c1)c1ccc2ccccc2c1O

InChI Key InChIKey=NGAGJZYKTLEWKK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50533243   

TargetAurora kinase B(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50533243(CHEMBL4514298)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of human recombinant His-tagged aurora B expressed in baculovirus infected Sf21 insect cells by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50533243(CHEMBL4514298)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged full-length aurora A expressed in Sf21 insect cells using ER-alpha as substrate after 25 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50533243(CHEMBL4514298)
Affinity DataIC50:  1.05E+5nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged full-length aurora A expressed in Sf21 insect cells using ER-alpha as substrate after 25 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Konkuk University

Curated by ChEMBL
LigandPNGBDBM50533243(CHEMBL4514298)
Affinity DataIC50:  8.53E+3nMAssay Description:Inhibition of human recombinant His-tagged aurora B expressed in baculovirus infected Sf21 insect cells by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed